Saturday, May 18, 2013

News for Brac 1 and Gene Testing

Latest News for Brac1 and Gene Testing


Women all over the world have heard the news that Angelina Jolie has undergone a double mastectomy to lower her risk of developing breast cancer.  Angelina Jolie is only 37 years old and women have valid questions including should they be tested for the gene?

To understand better, every woman has the BRCA1 and BRCA2 genes. We get two copies of each gene from our mother and father. They play a role in protecting the body against the development of cancer. I have heard women ask should they be tested for having the gene and for most women, that answer is no.

The Brac1 and Brac2 genes pose problems when there are mutations with those genes.  Most notably breast and ovarian cancer risks are raised.  If a woman has a mother or aunt that has died of breast or ovarian cancer at an early age, she should take steps to start a management program aimed at reducing her cancer risk and detecting cancers early when they are at their most treatable.  Even mutated genes do not necessarily mean you will contract cancer, it's your risk that goes up.  A mutated gene that is never triggered to express will remain healthy.  The environment, chemicals, pollution, smoking, bad diet...etc. are some of the triggers that can turn 'on' a mutation to express itself.
  •  Genetic counselors and other health care providers can help determine if testing is appropriate and who in the family should undergo testing first.  A woman needs as much information and education about lowering her risk.

  • Genetic testing for the Brac1 mutation are not advised for every women since the mutation affects only 5 percent of all breast cancers diagnosed. 

  • As always, eating healthy and predominately organic, exercising and not smoking are the healthiest things you can do for your body to minimize mutated genes from expressing.
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